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Symbol
Name
ID
Il22
interleukin 22
MGI:1355307
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased susceptibility to induced colitis
colitis
ear inflammation
decreased neutrophil cell number
abnormal circulating cytokine level
decreased circulating interleukin-1 alpha level
decreased circulating interleukin-12 level
decreased circulating interleukin-12b level
increased circulating interleukin-17 level
decreased circulating tumor necrosis factor level
abnormal cytokine secretion
increased interleukin-17 secretion
increased susceptibility to endotoxin shock
liver inflammation
lung inflammation
increased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to fungal infection
Availability Mouse Genotype
Il22tm1.1Lex/Il22tm1.1Lex
Il22tm1Flv/Il22tm1Flv
Il22tm1Jcrd/Il22tm1Jcrd *
Il22tm1Flv/Il22+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory